In the 1960s, medical researchers Thomas Holmes and Richard Rahe developed a checklist of stressful events. They appreciated the tricky point that any major change can be stressful. Bad events like "serious illness of a family member" were high on the list, but so were some helpful life-changing events like marriage.
When you take the Holmes-Rahe test you must remember that the score does not show how you deal with stress －it only shows how much you have to deal with. And we now know that the way you deal with these events dramatically (戏剧性的) affects your chances of staying healthy. By the early 1970s, hundreds of similar studies had followed Holmes and Rahe. And millions of Americans who work and live under stress worried over the reports. Somehow the research got boiled down to a memorable message. Women's magazines ran titles like "Stress causes illness".   
If you want to stay physically and mentally healthy the articles said avoid stressful events. But such simplistic advice is impossible to follow. Even if stressful events are dangerous , many — like the death of a loved one — are impossible to avoid. Moreover, any warning to avoid all stressful events is a prescription (处方) for staying away from chances as well as trouble. Since any change can be stressful, a person who wanted to be completely free of stress would never marry, have a child, take a new job or move. The idea that all stress makes you sick also takes no notice of a lot of what we know about people. It supposes we' re all vulnerable and not active in the face of the difficult situation. But what about human ability and creativity? Many come through periods of stress with more physical and mental strength than they had before. We also know that a long time without change or challenge can lead to boredom and physical and mental pressure.
41. The result of Holmes-Rahe’s medical research tells us _________________.
A. the way you deal with major events may cause stress
B. what should be done to avoid stress
C. what kind of event would cause stress
D. how to deal with sudden changes in life
42. The studies on stress in the early 1970s led to ___________________.
A. popular avoidance of stressful jobs      
B. great fear over the mental disorder
C. a careful research into stress-related illnesses
D. widespread worry about its harmful effects
43. The score of the Holmes-Rahe test shows ________________.
A. how you can deal with life-changing events  
B. how helpful events can change your life
C. how stressful a major event can be          
D. how much pressure you are under
44. Why is “such simplistic advice” (Line 1, Paragraph 3) impossible to follow?
A. No one can stay on the same job for long.    
B. No prescription is effective in reducing stress.
C. People have to get married someday.         
D. You could be missing chances as well.
45. According to the passage people who have experienced ups and downs may become _______.
A. nervous when faced with difficulties          B. physically and mentally tired
C. more able to deal with difficulties            D. cold toward what happens to them