22. Miss Alice didn’t respond ___ my question in public , ___ made me angry with her .
If better use is __________ of your spare time, you'll make great progress in your study.
English is difficult __________ well in a short time.
Paul doesn't have to be made __________. He always works hard.
The careless driver is __________ for the traffic accident that __________ yesterday.
It is often __________ that human beings are naturally equipped to speak.