________ a difficult situation, so you should send a message to him and give some advice to him .
— Do you mind my opening the window? It’s a bit hot in here. — ______________,as a matter of fact.
_____________ hard you try,it is difficult to lose weight without cutting down the amount you eat.
He was unhappy when he sold his violin.After all,he ____________ it for a very long time.
It is __________ you do rather than __________ you say __________ matters.
You can find Joe’s house easily because his house is _________ from others’ in the street by its pink walls and large windows.