Though _____ came that he was completely defeated, he didn’t lost heart.
___ China’s reform(改革)and opening up in fate 1978, its quick development has aroused worldwide attention.
We were told that we should follow the main road ___ we reached the central railway station.
Scientists say it may be five or six years ___ it is possible to test this medicine on human patients.
Tom’s and Joan’s ____ came to London last week.
You can hardly imagine the difficulty the woman had _____ her children.