After his wife died, he kept himself _____ from other people and the outside world,
The comments the expert made______ stock-market bothered him greatly,________him not fall asleep all night.
There has been a(n)________of gloom in the factory since it was announced that it would be closed.
The doctor thought the medicine was perfect,but it didn't ________the disease at all.
When will the new driving laws come into________?
Bill was doing a lot of physical exercise to build up his________.